Contact persons

Wang, Paul, Ph.D., Director

“The Molecular Imaging Laboratory research focuses on in vivo imaging using MRI, and optical fluorescent and bioluminescent imaging. In particular, we are interested in using molecular imaging techniques to study mechanisms of image contrast enhancement, improvement of sensitivity and specificity of tumor detection, and applications of diagnostics using small diseased animal models.

Research Focus Areas

Imaging of Small Animals Tumor Models (breast, prostate, melanoma, head and neck cancers)
Anatomical and functional Imaging (Alzheimer’s disease, cardiovascular disease)

Pharmacological Applications Drug Development, Translational Studies (muscle dystrophy, Schizophrenia)
In vivo Drug Metabolism (pharmacokinetics, multidrug interaction in CNS)

Nanomedicine Development of Nanoparticles (therapeutic / diagnostic agents, targeted drug delivery)
Safety and Toxicity of nanoparticle usage

Neuroscience Imaging Disorders of Mental Health (nicotine addiction, neurochemical anatomy)
Central/ Peripheral Nervous System (synaptic interaction of brain circuits and ganglia within the heart)

Ex vivo Cell Imaging Endocytosis of nanoparticles on intact Cells (mechanism of targeting)
Elucidation of Metabolic Pathways (molecular imaging)

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Services

  • 4 Imaging equipment access (Access service)
  • Imaging training (Training service) Provides training on instrumentation in the facility.
  • Protocol and experimental design (Support service)

Instrumentation/software

  • 4.7 Tesla (33 cm bore) Varian MRI (MRI Scanner) 4.7 Tesla magnetic resonance imaging system is suitable for the non-invasive high-resolution imaging of small animals.
  • Bruker 9.4 Tesla (89 mm vertical bore) MRI/MRS (MRI Scanner) A small bore vertical MRI that is suitable for non-invasive imaging of small animals.
  • Caliper IVIS spectrum live animal imaging system (In vivo imaging system)